Can you smoke cannabis sativa

Ellis, E. Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin. England, T. Cannabinoids in experimental stroke: a systematic review and meta-analysis. Blood Flow Metab. Esposito, G. Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NF-kappaB involvement. Faroqui, R. Acute carotid thrombosis and ischemic stroke following overdose of the synthetic cannabinoid K2 in a previously healthy young adult male.

Finsterer, J. Occipital stroke shortly after cannabis consumption. Fonseca, A. Drug abuse and stroke. Ford, T. Cannabis: an overview of its adverse acute and chronic effects and its implications. Drug Abuse Rev. Freeman, M. Neurology 81, — Gaoni Y and Mechoulam, R.

Isolation, structure, and partial synthesis of an active constituent of hashish. Garberg, H. Short-term effects of cannabidiol after global hypoxia-ischemia in newborn piglets. Garrett, C. Unusual case of tetrahydrocannabinol intoxication confirmed by radioimmunoassay. Gebremedhin, D. Geller, T. Cerebellar infarction in adolescent males associated with acute marijuana use. Pediatrics , e—e Goyal, H. Role of cannabis in cardiovascular disorders. Grotenhermen, F. Gruber, S.

Why so impulsive? White matter alterations are associated with impulsivity in chronic marijuana smokers. Gurney, S. Pharmacology, toxicology, and adverse effects of synthetic cannabinoid drugs.

PubMed Abstract Google Scholar. Hall, W. Adverse health effects of non-medical cannabis use. Lancet , — Han, J. Acute cannabinoids impair working memory through astroglial CB1 receptor modulation of hippocampal LTD. Hasin, D. US epidemiology of cannabis use and associated problems. Neuropsychopharmacology 43, — Haubrich, C. Recurrent transient ischemic attacks in a cannabis smoker. Hayakawa, K. Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism.

Hemachandra, D. Heavy cannabis users at elevated risk of stroke: evidence from a general population survey. Public Health 40, — Hendricks, B. Cerebrovascular operative anatomy: an immersive 3D and virtual reality description. Hagerstown 15, — Herkenham, M.

Cannabinoid receptor localization in brain. Hillard, C. Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic,U Hirapara, K. Synthetic cannabis use and stroke: a rising risk? Stroke 11, NP Hollister, L. Do plasma concentrations of delta 9-tetrahydrocannabinol reflect the degree of intoxication? Hossain, M. In vitro assessment of tobacco smoke toxicity at the BBB: do antioxidant supplements have a protective role?

BMC Neurosci. Inal, T. Acute temporal lobe infarction in a young patient associated with marijuana abuse: an unusual cause of stroke. World J. Ince, B. Both hemorrhagic and ischemic stroke following high doses of cannabis consumption.

Presse Med. Iring, A. Role of endocannabinoids and cannabinoid-1 receptors in cerebrocortical blood flow regulation.

Jamil, M. Stroke from vasospasm due to marijuana use: can cannabis synergistically with other medications trigger cerebral vasospasm? Jones, N. Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo. Jouanjus, E. Cannabis-related hospitalizations: unexpected serious events identified through hospital databases.

Cannabis use: signal of increasing risk of serious cardiovascular disorders. Heart Assoc. Jouroukhin, Y. Adolescent delta 9 -tetrahydrocannabinol exposure and astrocyte-specific genetic vulnerability converge on nuclear factor-kappaB-cyclooxygenase-2 signaling to impair memory in adulthood. Psychiatry 85, — Jung, J. Imaging 22, — Kaisar, M. New experimental models of the blood-brain barrier for CNS drug discovery.

Expert Opin. Drug Discovery 12, 89— Conventional and electronic cigarettes dysregulate the expression of iron transporters and detoxifying enzymes at the brain vascular endothelium: in vivo evidence of a gender-specific cellular response to chronic cigarette smoke exposure.

Kamat, A. Headache after substance abuse: a diagnostic dilemma. Karila, L. Acute and long-term effects of cannabis use: a review. Keskin, M. Acute myocardial infarction and ischemic stroke coexistence due to marijuana abuse in an adolescent. Koopman, K. An often unrecognized cause of thunderclap headache: reversible cerebral vasoconstriction syndrome.

Headache Pain 9, — Lawson, T. Stroke and transient ischaemic attacks in association with substance abuse in a young man. Lawston, J. Changes in hippocampal morphology following chronic treatment with the synthetic cannabinoid WIN 55, Leblanc, A. Cannabis and myocardial infarction without angiographic stenosis in young patient: guilty or not guilty?

A case report. Angeiol Paris 60, — Leker, R. Drug-induced hypothermia reduces ischemic damage: effects of the cannabinoid HU Stroke 34, — Lemberger, L.

Metabolism and disposition of deltatetrahydrocannabinol in man. Levine, A. Evidence for the risks and consequences of adolescent cannabis exposure. Child Adolesc. Psychiatry 56, — Long, L. Transmembrane domain Nrg1 mutant mice show altered susceptibility to the neurobehavioural actions of repeated THC exposure in adolescence.

Ma, Y. The phytocannabinoid Delta 9 -tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum. MacIntyre, J. Cannabinoid and lipid-mediated vasorelaxation in retinal microvasculature. Mack, A. The Science Beyond the Controversy. US: National Academies Press , Google Scholar. Maguire, M. Acute mutism: a useful lesson.

Marder, C. Multimodal imaging of reversible cerebral vasoconstriction syndrome: a series of 6 cases. AJNR Am. Marijuana Overview Marinella, M. Stroke after marijuana smoking in a teenager with factor V Leiden mutation. South Med. Mateo, I. Recurrent stroke associated with cannabis use. Psychiatry 76, — Cannabis and cerebrovascular disease. Neurologia 21, — Matochik, J.

Altered brain tissue composition in heavy marijuana users. McCarron, M. Cannabis and alcohol in stroke. Mecha, M.

Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: a role for A2A receptors. Mesec, A. Cerebrovascular disease associated with marijuana abuse: a case report.

Milroy, C. The histopathology of drugs of abuse. Histopathology 59, — Mohan, H. Conjugate deviation of the eyes after cannabis indica intoxication.

Mouzak, A. Murikinati, S. Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment.

Musshoff, F. Review of biologic matrices urine, blood, hair as indicators of recent or ongoing cannabis use. Drug Monit 28, — Naik, P. Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe? National Academies of Sciences, Engineering, and Medicine.

Is there a link between marijuana use and psychiatric disorders? Noskin, O. Diffuse cerebral vasoconstriction Call-Fleming syndrome and stroke associated with antidepressants. Neurology 67, — Nouh, A. Reversible cerebral vasoconstriction syndrome with multivessel cervical artery dissections and a double aortic arch. Ntlholang, O. Is intimal hyperplasia associated with cranial arterial stenosis in cannabis-associated cerebral infarction?

Stroke 10, E56—E An update on PPAR activation by cannabinoids. Chronic adolescent exposure to Deltatetrahydrocannabinol in COMT mutant mice: impact on psychosis-related and other phenotypes. Neuropsychopharmacology 35, — Omar, M. The effect of cannabis on oxidative stress and neurodegeneration induced by intrastriatal rotenone injection in rats. Owens, S. Oyinloye, O. Ischemic stroke following abuse of Marijuana in a Nigerian adult male.

Rural Pract. Parmentier-Batteur, S. Increased severity of stroke in CB1 cannabinoid receptor knock-out mice. Perucca, E. Cannabinoids in the treatment of epilepsy: hard evidence at last?

Epilepsy Res. Prasad, S. Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity. Redox Biol. Pun, P. Free Radic. Raheemullah, A.

Repeated thrombosis after synthetic cannabinoid use. Ray, W. Subarachnoid hemorrhage from a thoracic radicular artery pseudoaneurysm after methamphetamine and synthetic cannabinoid abuse: case report. Global Spine J. Renard, D. Brain haemorrhage and cerebral vasospasm associated with chronic use of cannabis and buprenorphine.

Cannabis-related myocardial infarction and cardioembolic stroke. Richter, J. A systematic review of the complex effects of cannabinoids on cerebral and peripheral circulation in animal models. Rivera-Olmos, V. Cannabis: effects in the central nervous system. Mex Seguro Soc. Rivers-Auty, J. The cannabinoid CB2 receptor agonist GW does not ameliorate brain damage induced by hypoxia-ischemia in rats. Robert, T. Reversible cerebral vasoconstriction syndrome identification of prognostic factors.

Rose, D. Neurology 85, — Rumalla, K. Recreational marijuana use and acute ischemic stroke: a population-based analysis of hospitalized patients in the United States. Association of recreational marijuana use with aneurysmal subarachnoid hemorrhage. Russmann, S. Lethal ischemic stroke after cisplatin-based chemotherapy for testicular carcinoma and cannabis inhalation.

Sajja, R. Altered Nrf2 signaling mediates hypoglycemia-induced blood-brain barrier endothelial dysfunction in vitro. PloS One 10, In vitro modulation of redox and metabolism interplay at the brain vascular endothelium: genomic and proteomic profiles of sulforaphane activity. Santos, A. But there are conflicting federal laws against using, growing, or selling marijuana — and people caught with it could face charges, including jail time.

Career problems. People charged under marijuana laws may end up with criminal records that hurt their plans for college or finding a job.

Drug testing. These days, employers often test for drug use as part of the hiring process. Marijuana can show up on a drug test for several weeks after it was last used. So people who use marijuana may find they don't get a job they want. Some companies do routine drug tests on employees, so people who use marijuana can lose their jobs.

The U. There's still a lot of discussion about the medical use of marijuana, though. THC and other cannabinoid pills are only available in some states and require a doctor's prescription. At the moment, there's not enough research to say for sure if smoking marijuana is any more helpful than taking THC or other cannabinoids as a pill. Scientists are still studying this.

People who use marijuana for a while can have withdrawal symptoms when they try to give it up. They may feel irritable, anxious, or depressed; have trouble sleeping; or not feel like eating. Marijuana withdrawal can be a bit like caffeine withdrawal: It's usually worse a day or two after someone stops using marijuana.

After that, withdrawal symptoms gradually decrease. They're usually gone a week or two after the person no longer uses the drug. Marijuana can be addictive. About 1 in 10 people who use the drug regularly can develop a "marijuana use disorder.

This is much more likely to happen in people who start using marijuana before age Originally from New York, she now calls San Diego home. She also writes a newsletter and hosts a podcast , both about cannabis culture. More of her work can be found here.

Sativa and indica are the two main types of cannabis plants. Here's how to find the right plant for your needs, strains to consider, and more. Find yourself one toke over the line and frantic to stop being high? These tips can help you come back down to earth. Weed doesn't go bad in the way perishable food does, but it can definitely degrade over time.

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Let go of the high vs. Take strains with a grain of salt. Use your nose. Consider edibles but start small. Know your dose. Let go of any past cannabis experiences.